Genomic Profile of Cervical Cancer in HPV Diagnosis.

Autores/as

DOI:

https://doi.org/10.70099/BJ/2025.02.01.8

Palabras clave:

cervical cancer, HPV, genes, tumor markers

Resumen

Cervical cancer arises from cellular abnormalities, usually caused by the presence of the human papillomavirus (HPV), specifically high-risk genotypes such as HPV-16 and HPV-18. However, some types of cancer are not associated with the virus, and their development originates from external factors. Most genes and proteins in cervical cancer are mutated or overexpressed by the viral oncoproteins E6 and E7. However, in cervical cancers not associated with HPV, these markers are altered due to mutations or loss of function of other genes that act on or influence them or the signaling pathways in which they participate.

The implementation of these biomarkers could facilitate early diagnosis and personalized treatment of different subtypes of cervical cancer, focusing on those that are not associated with the human papillomavirus.

Citas

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Publicado

2025-03-15

Cómo citar

Ortega Becerra, A. N., & Valenzuela Sánchez, G. P. (2025). Genomic Profile of Cervical Cancer in HPV Diagnosis. BioNatura Journal: Ibero-American Journal of Biotechnology and Life Sciences, 2(1), 12. https://doi.org/10.70099/BJ/2025.02.01.8

Número

Vol. 2 Núm. 1 (2025)

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