Terminological Rigor in Nanomedicine: Standardizing 'Nano' Descriptors for Reproducibility and Translational Success
Authors
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Hortensia Rodriguez
achay Tech Medicinal Chemistry Research Group (MedChem-YT), School of Chemical Science, Yachay University for Experimental Technology and Research (Yachay Tech), Yachay City of Knowledge, Urcuqui 100119, Ecuador
https://orcid.org/0000-0001-6910-5685
DOI:
https://doi.org/10.70099/BJ/2025.02.02.1Keywords:
nanomedicine, terminology standardization, drug delivery systems, scientific rigor, nanocarriers, size characterization, stimuli-responsive systems, targeted delivery, regulatory reproducibility, translational nanotechnology, EPR effect, nanoparticle characterization, academic integrityAbstract
The rapid growth of nanomedicine has revolutionized drug delivery innovations. Nevertheless, the scientific credibility is jeopardized by the uncritical use of "nano" terminology, which is frequently lacking in robust physicochemical or functional validation. This editorial denounces the misuse of terms such as "targeted delivery," "smart carriers," and "nanoparticles," which are frequently employed without experimental justification. We recommend concrete measures to standardize terminology, encouraging authors, journal editors, and educators to implement evidence-based definitions. To guarantee reproducibility, regulatory transparency, and successful clinical translation in nanomedicine, it is imperative to achieve rigorous semantic precision.
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Ruiz, A.; Suárez, M.; Mar
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