Stress Cardiomyopathy and Health Inequities: Lessons from the Global South

Authors

  • Plácido Argüelles Delgado Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Auenbruggerplatz 5, A-8036, Graz, Austria https://orcid.org/0000-0002-5600-8920

DOI:

https://doi.org/10.70099/BJ/2025.02.03.12

Keywords:

Takotsubo cardiomyopathy, broken heart syndrome, global health, stress-induced cardiomyopathy, cardiovascular equity, gender medicine.

Abstract

Takotsubo cardiomyopathy (TCM), also known as "broken heart syndrome," is a transient cardiac dysfunction typically triggered by emotional or physical stress. Although it has been extensively described in high-income countries, its recognition in low- and middle-income countries (LMICs) remains limited. The recently reported case from the Global South highlights how, even in the absence of advanced technologies such as cardiac MRI or 3D echocardiography, the combination of clinical acumen and basic diagnostic tools, including ECG, echocardiography, and coronary angiography, can lead to accurate diagnosis and favorable patient outcomes. Beyond its clinical aspects, this case emphasizes the psychosocial dimensions of TCM, especially its disproportionate impact on women and its association with emotional stressors in resource-constrained environments. The report underlines the urgent need to increase awareness, integrate gender-sensitive perspectives in acute cardiovascular care, and strengthen health systems to address stress-related cardiac conditions that may otherwise remain underdiagnosed.

References

1. Carbonell González M, Milo Alvarez M, Cabrera Rodríguez D, Yon Wong ML, Ramos Escobedo L, León Figueredo E. Takotsubo Cardiomyopathy Triggered by Emotional Stress in an Elderly Female. Bionatura Journal 2025;2(3):8. doi: 10.70099/BJ/2025.02.03.8.

2. Ghadri JR, Wittstein IS, Prasad A, et al. International expert consensus document on Takotsubo syndrome (Part I). Eur Heart J. 2018;39(22):2032–46. https://doi.org/10.1093/eurheartj/ehy076

3. Templin C, Ghadri JR, Diekmann J, et al. Clinical features and outcomes of Takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373(10):929–38. https://doi.org/10.1056/NEJMoa1406761

4. Deenen S, Ramnarain D, et al. Subarachnoid hemorrhage-related cardiomyopathy: an overview of Tako-Tsubo cardiomyopathy and related cardiac syndromes. Expert Review of Cardiovascular Therapy 2022;20(9): 733-745.

5. Santoro F, Núñez-Gil IJ, Stiermaier T, et al. Management of Takotsubo syndrome: a comprehensive review. Heart Fail Rev. 2021;26(6):1381–95. https://doi.org/10.1007/s10741-021-10114-x

6. Lyon AR, Bossone E, Schneider B, et al. Current state of knowledge on Takotsubo syndrome: a position statement of the Heart Failure Association of the ESC. Eur J Heart Fail. 2016;18(1):8–27. https://doi.org/10.1002/ejhf.424

7. Takotsubo cardiomyopathy: clinical features, diagnosis, and management [Internet]. 2025 [cited 2025 Jul 18]. Available from: https://www.uptodate.com/contents/takotsubo-cardiomyopathy-stress-cardiomyopathy-clinical-features-diagnosis-and-management

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Published

2025-09-15

How to Cite

Argüelles Delgado, P. (2025). Stress Cardiomyopathy and Health Inequities: Lessons from the Global South. BioNatura Journal: Ibero-American Journal of Biotechnology and Life Sciences, 2(3), 3. https://doi.org/10.70099/BJ/2025.02.03.12