Review of the pharmacological effects of Casimiroa edulis (white sapote)
Authors
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Eylin Misue Narváez Ortiz
Universidad Autónoma del Estado de Hidalgo, Pachuca de Soto, México
https://orcid.org/0009-0007-8809-7976
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Georgina Almaguer Vargas
Universidad Autónoma del Estado de Hidalgo, Pachuca de Soto, México
https://orcid.org/0000-0002-0396-752X
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José Ramón Montejano Rodríguez
Universidad Autónoma del Estado de Hidalgo, Pachuca de Soto, México
https://orcid.org/0000-0002-5744-381X
DOI:
https://doi.org/10.70099/BJ/2025.02.03.5Keywords:
Casimiroa edulis, white sapote, medicinal plant, hypotensive, sedativeAbstract
Medicinal plants are valuable natural resources worldwide. Several species have confirmed their therapeutic relevance throughout history, and their pharmacological effects have been validated by scientific research. Casimiroa edulis (white sapote) has been recognized for over 500 years for its sleep-inducing properties. Currently, it is widely used in Mexico as an antihypertensive. In vitro and in vivo studies, particularly on aqueous extracts from leaves and seeds, have demonstrated a broad spectrum of pharmacological activities: anticonvulsant, anxiolytic, sedative, hypnotic, antidepressant, hypoglycemic, antihypertensive, anticoagulant, anti-inflammatory, antimutagenic, cytotoxic, antimicrobial, and antioxidant. This diversity makes white sapote an appealing therapeutic alternative that warrants further research.
References
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